How Addison’s Disease Affects Dogs

Addison’s Disease is an endocrine disorder caused by inadequate production of corticosteroid hormones by one or both of the dog’s adrenal glands. The symptoms of this disease typically wax and wane, which means that they come and go, and they can range from mild to extremely severe and can vary over time. Dogs with Addison’s tend to feel lousy in waves, especially when they are under stress. They may experience belly pain, nausea, vomiting, diarrhea, weakness, depression and other unpleasant symptoms of systemic illness.

Symptoms of Addison’s Disease

While the signs of this disease are fairly non-specific and can be caused by a number of different disorders, most watchful owners usually can spot the signs of Addison’s in their dogs, even though they may not know what is causing them to occur. Outward signs of Addison’s in dogs usually include one or more of the following:

Another potential sign of Addison’s Disease is when a dog unexpectedly deviates from its normal activities or routines, for no apparent reason. For instance, if a dog is reluctant to jump on a couch or bed that it usually leaps on happily, the owner should pay attention, because pain and muscle weakness can accompany Addison's Disease and could be contributing to the dog’s discomfort. All of the above signs are commonly associated with other conditions. However, the symptoms of Addison’s usually become more frequent and severe over time, as the dog’s body becomes increasingly damaged from the effects of the disease. One of the hallmarks of Addison's is that the signs worsen with stress. By the time a dog is diagnosed with this disease, emergency medical treatment normally is necessary. Once a dog has been stabilized, the attending veterinarian can make a proper assessment of its condition and status, and proper treatment protocols can be implemented.

Predispositions

Addison’s Disease is most commonly seen in young to middle-aged female dogs averaging between 4 and 6 years of age, although dogs of any age or gender can be affected. It is not entirely clear whether there are definitive breed predispositions for this disease. However, some authorities suggest that Great Danes, West Highland White Terriers, Bearded Collies, Standard Poodles, Rottweilers, Basset Hounds, Labrador Retrievers, Nova Scotia Duck Tolling Retrievers, Leonbergers, Soft Coated Wheaten Terriers and Portuguese Water Dogs are at an increased risk. Because of this, a genetic component is strongly suspected.